MIT DHIVE Inflammatory Bowel Disease track

A Deep Dive into Healthcare Entrepreneurship


SUMMER 2022 DHIVE IBD Track

The MIT DHIVE Inflammatory Bowel Disease (IBD) Track, offered in partnership with the MIT Center for Microbiome Informatics and Therapeutics (CMIT), is an exciting internship opportunity focused on developing student-led entrepreneurial solutions that provide personalized preventative medicine in chronic diseases.

The CMIT IBD Tracker clinical study aims to predict flare-ups in patients suffering from Inflammatory Bowel Disease (IBD), empowering patients and transforming the way we approach the maintenance of chronic disease.

Participants will learn from IBD clinical care and microbiome-based healthcare innovation experts about key needs and challenges related to IBD, engage in brainstorming and ideation activities, and learn how to transform ideas into technical and marketing plans. This track is open to both undergraduate and graduate students.

 

MIT CMIT IBDTracker Study

Making new drugs to treat disease is a difficult process that takes many years and is rarely successful. But what if patients could make better use of the drugs we already have? Could knowing when symptoms are going to flare up in advance give patients the edge they need to minimize the impacts of disease, or prevent episodes altogether?

That’s the premise of a new study by CMIT called IBDTracker which aims to predict flare ups in patients suffering from Inflammatory Bowel Disease (IBD). A N=100 patient trial is currently underway that will collect the pilot data that will enable advance prediction of IBD flare ups, empowering patients and transforming the way we approach maintenance of chronic disease. 

Source: https://microbiome.mit.edu/research/flagship-project/

Seeking Innovative Entrepreneurial Solutions to Predict IBD Flare Ups

The CMIT is seeking teams interested in taking the knowledge learned from the IBDTracker study and expand it to 1000s of participants nationally. The current implementation of IBDTracker includes a mobile app, microbiome sequencing, biomarker testing, and a wearable device. Any or all of these can be part of the next phase of the trial.

This nation-wide scale up can be implemented in the context of a commercial or non-profit entity and should include technical and business solutions to achieve the following goals:

  • reducing materials & service costs (microbiome sequencing, biomarker quantitation)

  • reducing patient burden (ease-of-use for sample collection and/or in-home diagnostic devices)

  • improving patient experience (UI/UX, real-time data return)

Teams will work to produce a technical plan, as well as a business and marketing plan for providing predictive technology for IBD patient care. Initial startup funds are available from CMIT for compelling business plans and participants will gain access to CMIT's network of world-renowned experts in IBD clinical care and microbiome-based healthcare innovation.


Recent Program Speakers

Most DHIVE expert talks are recorded. We are happy to share any recording with DHIVE participants/potential participants. Email dhive-ops@mit.edu with your request.

CMIT and the IBD Tracker Trial
Eric Alm, PhD | Professor of Biological Engineering, MIT | Co-Director for the Center of Microbiome Informatics and Therapeutics at MIT; January 10th, 2022

Diagnostic and therapeutic opportunities in inflammatory bowel disease
Sathish Subramanian, MD, PhD | Gasteroentrenology Fellow | MGH; January 11th, 2022

The Complexities of Clinical Research: We’re Only Human!
Helena Lau, MSPH & Sean Kim | The Xavier Lab at MGH and the Broad Institute | the MGH Crohn's and Colitis Center; January 11th, 2022

IBD Tracker: identifying biomarkers in the gut microbiome predictive of an IBD flare
Marjolein A.Y. Klaassen | University of Groningen and University Medical Center of Groningen; January 12th, 2022

Monitoring an IBD patient in remission
Jason Zhang, MD | Clinical Fellow in Pediatrics | Boston Children's Hospital; January 12th, 2022

GutSee: Building an engaging user experience for patients in a longitudinal IBD study
Ben Cooley, Duyen Nguyen, and Andrew Tang | Pattern, The Broad Institute of MIT and Harvard; January 13th, 2022

Count Me In: Partnering with Patients to Accelerate the Pace of Cancer Discoveries
Corrie Painter, PhD | Associate Director of Operations and Scientific Outreach, Cancer Program, Broad Institute | Associate Director, Count Me In; January 14th, 2022